Collision induced dissociations of deprotonated peptides. Dipeptides and tripeptides containing proline
β Scribed by Russell J. Waugh; John H. Bowei; Michael L. Gross; David Vollmer
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 555 KB
- Volume
- 133
- Category
- Article
- ISSN
- 0168-1176
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π SIMILAR VOLUMES
## Abstract Deprotonated dipeptides, on collisional activation, fragment by the characteristic process NH~2~CH(R^1^) CONHCH(R^2^)CO~2~^β^ β NH~2~^β^C(R^1^)CONHCH(R^2^)CO~2~H β ^β^NHCH(R^2^)CO~2~H + NH~2~C(R^1^)ο£ΎCο£ΎO, when R^1^ and R^2^ = H or alkyl. However, when one of the constituent amino acids i
The characteristic coUisionLinduced dissociations of (M -HI-ions of dipeptides and tripeptides involve proton transfer to the carboxylate centre as a prelude to fragmentation. Dipeptides show the process + NH,C(R')=C=O (R = H or alkyl) while tripeptides show the analogous processes NH,CH(R')CONHCH(R
## Abstract The collisionβinduced dissociation (CID) fragmentation reactions of a variety of deprotonated peptides containing proline have been studied in detail using MS^2^ and MS^3^ experiments, deuterium labelling and accurate mass measurements when necessary. The [Mο£ΏHο£ΏCO~2~]^β^ (a~2~) ion deriv