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Collagen type V supports the malignant phenotype of pancreatic cancer cell lines through the integrin signaling pathway

✍ Scribed by Berchtold, Sonja; Reithmeier, Anja; Haneder, Susanne; Esposito, Irene


Book ID
122795690
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
48 KB
Volume
13
Category
Article
ISSN
1424-3903

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## Abstract The authors have previously demonstrated that α~2~β~1~ integrin‐mediated pancreatic cancer cell adhesion to Type I collagen is Mg^2+^‐dependent, inhibited by Ca^2+^, and that this integrin, purified from cell lysates using Type I‐collagen‐sepharose in Mg^2+^, can be eluted with Ca^2+^.