The α2β1 integrin regulates the malignant phenotype on type I collagen in pancreatic cancer cell lines
✍ Scribed by J.J. Grzesiak; L.J. Deftos; A.R. Moossa; M. Bouvet
- Book ID
- 116702294
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 127 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0022-4804
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## Abstract The authors have previously demonstrated that α~2~β~1~ integrin‐mediated pancreatic cancer cell adhesion to Type I collagen is Mg^2+^‐dependent, inhibited by Ca^2+^, and that this integrin, purified from cell lysates using Type I‐collagen‐sepharose in Mg^2+^, can be eluted with Ca^2+^.
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