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Codon 89 polymorphism in the human 5 α -reductase gene in primary breast cancer

✍ Scribed by Scorilas, A; Bharaj, B; Giai, M; Diamandis, E P

Book ID
111724476
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
212 KB
Volume
84
Category
Article
ISSN
0007-0920

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## Abstract In the prostate, the enzyme encoded by the __SRD5A2__ gene (5α‐reductase) converts testosterone to dihydrotestosterone, a potent androgen that has been hypothesized to play a role in the genesis of prostate cancer. Several polymorphisms have been identified in the __SRD5A2__ gene, inclu