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Single Nucleotide Polymorphisms in the Hypoxia-inducible Factor-1α (HIF-1α) Gene in Human Sporadic Breast Cancer

✍ Scribed by Isil Apaydin; Ece Konac; H. Ilke Onen; Murat Akbaba; Ercument Tekin; Abdullah Ekmekci


Book ID
113467185
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
390 KB
Volume
39
Category
Article
ISSN
0188-4409

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## Abstract With an incidence of about 300 000 new cases colorectal cancer (CRC) is the second leading cause of cancer‐related death in Europe and the United States. Environmental and genetic factors influence CRC risk. Hypoxia‐inducible factor‐1 (HIF‐1), a heterodimeric protein composed of two sub