## Abstract ## Background. Laser cordectomy is gaining popularity for treatment of early glottic carcinoma, but little is known about vocal and quality of life (QOL) outcomes as a function of extent of resection. We prospectively examined QOL and vocal function of patients with carcinoma in situ (
CO2 laser therapy in Tis and T1 glottic cancer: Indications and results
β Scribed by Lucio Rucci; Paolo Romagnoli; Jacopo Scala
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 114 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1043-3074
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β¦ Synopsis
Abstract
Background.
Laser cordectomy for glottic cancer is still hampered by recurrence, which is more frequent upon anterior commissure (AC) involvement. Analysis of results may be a step to improve the efficacy of this therapy for early glottic cancer.
Methods.
In all, 81 patients who underwent surgery with CO~2~ laser for Tis and T1, AC0 to AC2 glottic carcinoma were followed up to 55 months.
Results.
The incidence of recurrence increased significantly with T and AC classifications. The diseaseβfree interval decreased with increasing T and AC classifications and with increasing severity of histology, but only the AC classification appeared significant. Recurrences occurred in 5 of 35 patients upon type I and type II cordectomy, in 16 of 24 patients upon type V cordectomy, and never upon type III and IV cordectomy.
Conclusions.
Type I to type IV cordectomy, when indicated, can achieve radical treatment of most T1 glottic cancer. Type V cordectomy requires that any suspicion of cartilage invasion, even microscopic, be excluded. Β© 2009 Wiley Periodicals, Inc. Head Neck, 2010
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