✦ LIBER ✦

Results of radiation therapy in early glottic carcinoma (T1 T2 N0)

✍ Scribed by Dr. Moshe Stein; Edward Rosenblatt; Abraham Kuten; Dr. Yoram Cohen

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 415 KB
Volume: 40
Category: Article
ISSN: 0022-4790
DOI: 10.1002/jso.2930400308

No coin nor oath required. For personal study only.

✦ Synopsis

Glottic carcinoma is curable by either surgery or radiotherapy. A total of 60 patients were treated by radiation alone at the Northern Israel Oncology Center, Rambam Medical Center, Haifa, between 1970 and 1980. Twentynine (48%) were classified as TI No and 31 (52%) as T2 No. All patients received radiotherapy primarily with curative intent, with surgery reserved for recurrences. The 5-year actuarial survival for all patients was 90% and actuarial disease-free survival was 95%. In ten patients (17%) there was local failure, and five of them were salvaged by surgery. There were no significant acute or long-term complications of radiation. Factors influencing treatment outcome (anterior commissures involvement, degree of differentiation, treatment volume, and technique of irradiation) and the occurrence of second primary malignancies are discussed.

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