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CO2 Is Required for the Assembly of the Binuclear Metal Center of Phosphotriesterase

โœ Scribed by Hong, Suk-Bong; Kuo, Jane M.; Mullins, Leisha S.; Raushel, Frank M.

Book ID
126402145
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
271 KB
Volume
117
Category
Article
ISSN
0002-7863

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Phosphotriesterase (PTE) is a zinc metalloenzyme that catalyzes the hydrolysis of an extensive array of organophosphate pesticides and mammalian acetylcholinesterase nerve agents. Although the three-dimensional crystal structure of PTE has been solved (M. M. Benning et al., Biochemistry 34:7973-7978