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Utilization of Copper as a Paramagnetic Probe for the Binuclear Metal Center of Phosphotriesterase

✍ Scribed by M.Y. Chae; G.A. Omburo; P.A. Lindahl; F.M. Raushel

Book ID
115565443
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
704 KB
Volume
316
Category
Article
ISSN
0003-9861

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Phosphotriesterase (PTE) is a zinc metalloenzyme that catalyzes the hydrolysis of an extensive array of organophosphate pesticides and mammalian acetylcholinesterase nerve agents. Although the three-dimensional crystal structure of PTE has been solved (M. M. Benning et al., Biochemistry 34:7973-7978