𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Co production of 2,6-[18F] difluoroDOPA during electrophilic synthesis of 6-[18F]fluoro-l-DOPA

✍ Scribed by Kentaro Hatano; Kiichi Ishiwata; Touru Yanagisawa


Book ID
117688133
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
280 KB
Volume
23
Category
Article
ISSN
0969-8051

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Alternative solvents for electrophilic s
✍ Sarita Forsback; Olli Eskola; JΓΆrgen Bergman; Merja Haaparanta; Olof Solin πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 95 KB πŸ‘ 1 views

## Abstract Owing to the ozone layer‐depleting properties of chlorofluorocarbon compounds, alternative solvents for electrophilic fluorination reactions are desirable. Chloroform, dichloromethane, acetone or their deuterated analogues were examined as substitutes for Freon‐11 in the electrophilic s

Trifluoromethanesulfonic acid, an altern
✍ Babak Behnam Azad; Raman Chirakal; Gary J. Schrobilgen πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 French βš– 133 KB πŸ‘ 1 views

Previous work from this laboratory has shown that the direct fluorination of 3, 4-dihydroxy-phenyl-lalanine (l-DOPA) in anhydrous HF (aHF) or BF 3 /HF with F 2 is an efficient method for the synthesis of 6-fluoro-l-DOPA. Since then, 18 F-labeled 6-fluoro-l-DOPA ([ 18 F]6-fluoro-l-DOPA) has been used

Regioselective radiofluorodestannylation
✍ Mohammad Namavari; Allyson Bishop; N. Satyamurthy; Gerald Bida; Jorge R. Barrio πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science βš– 975 KB

A protected 6-trimethylstannyl dopa derivative 6 has been synthesized for the first time as a precursor for the preparation of 6-[18F]fluoro-L-dopa. The tin derivative 6 readily reacted with electrophilic radiofluorinating agents such as [18F]F2 and [18F]AcOF. The [18F]fluoro intermediate 7 was easi