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CNS chemokines, cytokines, and dendritic cells in autoimmune demyelination

✍ Scribed by Benjamin M. Segal

Book ID
119301565
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
175 KB
Volume
228
Category
Article
ISSN
0022-510X

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## Experimental autoimmune encephalomyelitis (EAE) has served as a model for human demyelinating diseases, including multiple sclerosis. EAE is mediated by CD4 Ψ‰ T lymphocytes of the TH1 subset. These T cells produce inflammatory cytokines and chemokines that are associated with pathogenicity. The