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CNP and DPYSL2 mRNA Expression and Promoter Methylation Levels in Brain of Alzheimer's Disease Patients

✍ Scribed by Natalia Silva, Patrícia ;Furuya, Tatiane Katsue ;Sampaio Braga, Ianna ;Rasmussen, Lucas Trevizani ;de Labio, Roger Willian ;Bertolucci, Paulo Henrique ;Chen, Elizabeth Suchi ;Turecki, Gustavo ;Mechawar, Naguib ;Payão, Spencer Luiz ;Mill, Jonathan ;Cardoso Smith, Marília

Book ID
115480071
Publisher
IOS Press
Year
2012
Tongue
English
Weight
330 KB
Volume
33
Category
Article
ISSN
1387-2877

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## Abstract We developed a novel quantitative assay to test the hypothesis that defects in DNA cytosine methylation might be responsible for the brain chromatin abnormalities and transcriptional alterations observed in patients with Alzheimer's disease (AD). We found no significant difference in pe