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Analysis of HSPA8 and HSPA9 mRNA Expression and Promoter Methylation in the Brain and Blood of Alzheimer's Disease Patients

✍ Scribed by Silva, Patricia Natalia ;Furuya, Tatiane Katsue ;Braga, Ianna Lacerda ;Rasmussen, Lucas Trevizani ;Labio, Roger Willian ;Bertolucci, Paulo Henrique ;Chen, Elizabeth Suchi ;Turecki, Gustavo ;Mechawar, Naguib ;Payão, Spencer Luiz ;Mill, Jonathan ;Smith, Marília Cardoso

Book ID
121212795
Publisher
IOS Press
Year
2013
Tongue
English
Weight
127 KB
Volume
38
Category
Article
ISSN
1387-2877

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## Abstract We developed a novel quantitative assay to test the hypothesis that defects in DNA cytosine methylation might be responsible for the brain chromatin abnormalities and transcriptional alterations observed in patients with Alzheimer's disease (AD). We found no significant difference in pe