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Analysis of SNAP25 mRNA expression and promoter DNA methylation in brain areas of Alzheimer’s Disease patients

✍ Scribed by T.K. Furuya; P.N.O. Silva; S.L.M. Payão; P.H.F. Bertolucci; L.T. Rasmussen; R.W. De Labio; I.L.S. Braga; E.S. Chen; G. Turecki; N. Mechawar; J. Mill; M.A.C. Smith

Book ID
116789713
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
133 KB
Volume
220
Category
Article
ISSN
0306-4522

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## Abstract We developed a novel quantitative assay to test the hypothesis that defects in DNA cytosine methylation might be responsible for the brain chromatin abnormalities and transcriptional alterations observed in patients with Alzheimer's disease (AD). We found no significant difference in pe