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Clozapine and sulpiride up-regulate dopamine D3 receptor mRNA levels

✍ Scribed by Paul R. Buckland; Michael C. O'Donovan; Peter McGuffin


Book ID
116037558
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
514 KB
Volume
32
Category
Article
ISSN
0028-3908

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Up-regulation of D3 dopamine receptor mR
✍ Wei Wang; Kyu-Hee Hahn; John F. Bishop; Da-Qing Gao; Pedro A. Jose; M. Maral Mou πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 414 KB

The effects of 14 days neuroleptic treatment on the expression of the D3 dopamine receptor gene was investigated in rats using a sensitive polymerase chain reaction assay. In olfactory tubercle, D3 mRNA levels increased following haloperidol (40%), pimozide (56%), and sulpiride (63%) administration,