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Up-regulation of D3 dopamine receptor mRNA in the nucleus accumbens of human cocaine fatalities

✍ Scribed by David M Segal; Carlos T Moraes; Deborah C Mash


Book ID
117386811
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
327 KB
Volume
45
Category
Article
ISSN
0169-328X

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Up-regulation of D3 dopamine receptor mR
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The effects of 14 days neuroleptic treatment on the expression of the D3 dopamine receptor gene was investigated in rats using a sensitive polymerase chain reaction assay. In olfactory tubercle, D3 mRNA levels increased following haloperidol (40%), pimozide (56%), and sulpiride (63%) administration,