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Cloning, sequencing and analysis of the yeastS. uvarum ERG10gene encoding acetoacetyl CoA thiolase

✍ Scribed by Sylvie Dequin; Remi Gloeckler; Christopher J. Herberte; Françoise Boutelet


Publisher
Springer-Verlag
Year
1988
Tongue
English
Weight
691 KB
Volume
13
Category
Article
ISSN
0172-8083

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We analyzed the mitochondrial acetoacetyl-CoA thiolase gene (T2) by Southern blotting. Fifteen unrelated healthy individuals and members of five families with 3-ketothiolase deficiency (3KTD) were analyzed. We found a TaqI polymorphism, the heterozygosity of which was calculated to be 0.5 among heal