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Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

โœ Scribed by March, Carl J.; Mosley, Bruce; Larsen, Alf; Cerretti, Douglas Pat; Braedt, Gary; Price, Virginia; Gillis, Steven; Henney, Christopher S.; Kronheim, Shirley R.; Grabstein, Kenneth


Book ID
109739371
Publisher
Nature Publishing Group
Year
1985
Tongue
English
Weight
833 KB
Volume
315
Category
Article
ISSN
0028-0836

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โœ Eisenberg, Stephen P.; Evans, Ron J.; Arend, William P.; Verderber, Evie; Brewer ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 826 KB

Human monocytes induced with adherent IgG secrete an interleukin-1 receptor antagonist which could be important for the in vivo regulation of IL-1 activity. A complementary DNA for this molecule has been isolated from a human monocyte library. Analysis of monocyte RNA indicates that the gene is tran