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Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist

✍ Scribed by Eisenberg, Stephen P.; Evans, Ron J.; Arend, William P.; Verderber, Evie; Brewer, Michael T; Hannum, Charles H.; Thompson, Robert C.

Book ID
109762519
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
826 KB
Volume
343
Category
Article
ISSN
0028-0836

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Primary structure and functional express
Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist
✍ Eisenberg, Stephen P.; Evans, Ron J.; Arend, William P.; Verderber, Evie; Brewer πŸ“‚ Article πŸ“… 1990 πŸ› Nature Publishing Group 🌐 English βš– 826 KB

Human monocytes induced with adherent IgG secrete an interleukin-1 receptor antagonist which could be important for the in vivo regulation of IL-1 activity. A complementary DNA for this molecule has been isolated from a human monocyte library. Analysis of monocyte RNA indicates that the gene is tran