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Cloning of the putative tumour suppressor gene for hereditary multiple exostoses (EXT1)

✍ Scribed by Ahn, Jung; Lüdecke, Hermann-Josef; Lindow, Steffi; Horton, William A.; Lee, Brendan; Wagner, Michael J.; Horsthemke, Bernhard; Wells, Dan E.


Book ID
109918266
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
873 KB
Volume
11
Category
Article
ISSN
1061-4036

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Molecular basis of multiple exostoses: m
✍ Wim Wuyts; Wim Van Hul 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 232 KB 👁 3 views

Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by the formation of exostoses, which are cartilage-capped bony protuberances mainly located on long bones. Two genes, EXT1 and EXT2, and at least one other unidentified gene, are known to be involved in the formation