Mutations in the EXT1 and EXT2 Genes in Hereditary Multiple Exostoses
✍ Scribed by Wuyts, Wim (author);Van Hul, Wim (author);De Boulle, Kristel (author);Hendrickx, Jan (author);Bakker, Egbert (author);Vanhoenacker, Filip (author);Mollica, Florindo (author);Lüdecke, Hermann Josef (author);Sayli, Bekir Sitki (author);Pazzaglia, Ugo E. (author);Mortier, Geert (author);Hamel, Ben (author);Conrad, Ernest U. (author);Matsushita, Mark (author);Raskind, Wendy H. (author);Willems, Patrick J. (author)
- Book ID
- 117852299
- Publisher
- Cell Press
- Year
- 1998
- Tongue
- English
- Weight
- 327 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/301726
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📜 SIMILAR VOLUMES
Hereditary multiple exostoses (EXT) is an autosomal dominant disorder characterized by the formation of exostoses, which are cartilage-capped bony protuberances mainly located on long bones. Two genes, EXT1 and EXT2, and at least one other unidentified gene, are known to be involved in the formation
94°C for 5min; 35 cycles of 94°C for 20sec, 55°C for 30 sec and 72°C for 45 sec; and 72°C for 30 min.