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Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

✍ Scribed by Van Tol, Hubert H. M.; Bunzow, James R.; Guan, Hong-Chang; Sunahara, Roger K.; Seeman, Philip; Niznik, Hyman B.; Civelli, Olivier


Book ID
109773790
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
598 KB
Volume
350
Category
Article
ISSN
0028-0836

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Cloning of the gene for a human dopamine
✍ Van Tol, Hubert H. M.; Bunzow, James R.; Guan, Hong-Chang; Sunahara, Roger K.; S πŸ“‚ Article πŸ“… 1991 πŸ› Nature Publishing Group 🌐 English βš– 598 KB

Dopamine receptors belong to the family of G protein-coupled receptors. On the basis of the homology between these receptors, three different dopamine receptors (D1, D2, D3) have been cloned. Dopamine receptors are primary targets for drugs used in the treatment of psychomotor disorders such as Park