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Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor

โœ Scribed by Siusaidh K Schlachter; Toni J Poel; Charles F Lawson; Dac M Dinh; Mary E Lajiness; Arthur G Romero; Susan A Rees; J.Neil Duncan; Martin W Smith


Book ID
119413698
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
169 KB
Volume
322
Category
Article
ISSN
0014-2999

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Cloning of the gene for a human dopamine
โœ Van Tol, Hubert H. M.; Bunzow, James R.; Guan, Hong-Chang; Sunahara, Roger K.; S ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 598 KB

Dopamine receptors belong to the family of G protein-coupled receptors. On the basis of the homology between these receptors, three different dopamine receptors (D1, D2, D3) have been cloned. Dopamine receptors are primary targets for drugs used in the treatment of psychomotor disorders such as Park