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Clonal origin of Philadelphia chromosome negative cells with trisomy 8 appearing during the course of α-interferon therapy for Ph positive chronic myelocytic leukemia

✍ Scribed by Takeshi Ariyama; Johji Inazawa; Yoshiki Uemura; Naoki Kakazu; Taira Maekawa; Fumiaki Urase; Kiyohiro Irimajiri; Atsushi Horiuchi; Yusuke Nakamura; Tatsuo Abe

Book ID
113253404
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
360 KB
Volume
81
Category
Article
ISSN
0165-4608

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Trisomy 8 in philadelphia chromosome (ph
Trisomy 8 in philadelphia chromosome (ph1)-negative cells in the course of ph1-positive chronic myelocytic leukemia
✍ Monica Casali; Fabrizio Truglio; Emanuela Maserati; Francesco Pasquali; Giuseppe 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 196 KB

## Abstract A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph^1^), cells with trisomy 8