Clonal chromosome changes including a del(6q) in a possible early lymphoma
β Scribed by N.B. Atkin; Z. Jackson
- Book ID
- 114136039
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 410 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0165-4608
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π SIMILAR VOLUMES
W e report a lymphocytic lymphoma showing a combination of two characteristic neoplasia-associated chromosomal changes: trisomy 12, commonly observed in chronic lymphocytic leukemia and lymphocytic lymphoma, and t( I822)(q21;q I I), a variant form of the t( 14;18)(q32;q21) found in most follicular l
## Abstract Regional deletions of 6q are frequent karyotypic alterations in malignant lymphoma and are associated with an adverse clinical outcome. One such region of recurrent deletion is 6q16βq21; however, the specific genes affected have not been identified. Our objective in this study was to id