Clomipramine and Imipramine Suppress Clinical Signs and T and B Cell Response to Myelin Proteins in Experimental Autoimmune Neuritis in Lewis Rats
✍ Scribed by Jie Zhu; Bengt-Olof Bengtsson; Eilhard Mix; Lena Ekerling; Lars-Håkan Thorell; Tomas Olsson; Hans Link
- Book ID
- 115621574
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 154 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0896-8411
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Experimental autoimmune neuritis (EAN) is a CD4 ؉ T cell-mediated, inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre ´syndrome (GBS) in humans. Various mouse and rat strains show different susceptibilities to EAN that can be induced b
Experimental autoimmune neuritis (EAN) is a CD4 1 Tcell-mediated inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre ´syndrome (GBS) in humans. Various rat strains show different susceptibility to EAN. We examined PNS myelin-induced T-a