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Experimental autoimmune myositis in the Lewis rat: lack of spontaneous T-cell apoptosis and therapeutic response to glucocorticosteroid application

✍ Scribed by C Schneider; Y Matsumoto; K Kohyama; K.V Toyka; H.P Hartung; R Gold


Book ID
114137145
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
305 KB
Volume
107
Category
Article
ISSN
0165-5728

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Experimental autoimmune neuritis (EAN) is a CD4 Ψ‰ T cell-mediated, inflammatory demyelinating disease of the peripheral nervous system (PNS) that serves as a model for Guillain-Barre Β΄syndrome (GBS) in humans. Various mouse and rat strains show different susceptibilities to EAN that can be induced b