Clipped representations of fourier-transform ion-cyclotron resonance mass spectra

✍ Scribed by Annjia T. Hsu; Alan G. Marshall; Tom L. Ricca

• Publisher: Elsevier Science
• Year: 1985
• Tongue: English
• Weight: 918 KB
• Volume: 178
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/s0003-2670(00)86256-x

✦ Synopsis

Because of its high mass resolution over a wide mass range, a Fourier transform/mass spectrometry (F.t./m.s.) experiment may generate very large spectral data sets (>64 K each), creating severe data storage problems for g.c./F.t./m.s. and for mass spectral library storage, search and retrieval. Fortunately, the stored experimental data need not be highly precise. In this paper, it is shown that useful mass spectra can be produced from time-domain F.t./m.s. data that have been clipped to only 1 bit/word, thereby offering a potential reduction by a factor of >20 in data storage requirement. In many cases, mass spectral resolution can actually be enhanced by the clipping process. Finally, it is shown that a compound can be identified quickly and accurately by comparison of its clipped representation with similarly clipped data for library compounds. 'Also a member of the Department of Biochemistry.