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Clinical Trial Design for Target Specific Anticancer Agents

✍ Scribed by Ronald Hoekstra; Jaap Verweij; Ferry A.L.M. Eskens

Book ID: 110438078
Publisher: Springer US
Year: 2003
Tongue: English
Weight: 90 KB
Volume: 21
Category: Article
ISSN: 0167-6997
DOI: 10.1023/a:1023581731443

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The currently understood function for Ras in signal transduction is in mediating the transmission of signals from external growth factors to the cell nucleus. Mutated forms of this GTP-binding protein are found in 30% of human cancers with particularly high prevalence in colon and pancreatic carcino