Fusion processing of itraconazole solid
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James C. DiNunzio; Chris Brough; Dave A. Miller; Robert O. Williams III; James W
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Article
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2010
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John Wiley and Sons
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English
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KinetiSol Dispersing (KSD) is a novel high energy manufacturing process investigated here for the production of pharmaceutical solid dispersions. Solid dispersions of itraconazole (ITZ) and hypromellose were produced by KSD and compared to identical formulations produced by hot melt extrusion (HME).