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Clinical significance of pretreatment serum amphiregulin and transforming growth factor-α, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer

✍ Scribed by Katsuhiro Masago; Shiro Fujita; Yukimasa Hatachi; Akiko Fukuhara; Keiichiro Sakuma; Masataka Ichikawa; Yung Haku Kim; Tadashi Mio; Michiaki Mishima

Book ID: 108584311
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 175 KB
Volume: 99
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2008.00931.x

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## Abstract ## Background and Objectives In this paper we examined the influence of epidermal growth factor receptor (EGFR) gene mutations on EGFR expression, downstream mediators, and survival in patients with non‐small cell lung cancer (NSCLC). ## Methods We retrospectively analyzed the tumors