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Clinical significance of pretreatment serum amphiregulin and transforming growth factor-α, and an epidermal growth factor receptor somatic mutation in patients with advanced non-squamous, non-small cell lung cancer

✍ Scribed by Katsuhiro Masago; Shiro Fujita; Yukimasa Hatachi; Akiko Fukuhara; Keiichiro Sakuma; Masataka Ichikawa; Yung Haku Kim; Tadashi Mio; Michiaki Mishima


Book ID
108584311
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
175 KB
Volume
99
Category
Article
ISSN
1347-9032

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## Abstract ## Background and Objectives In this paper we examined the influence of epidermal growth factor receptor (EGFR) gene mutations on EGFR expression, downstream mediators, and survival in patients with non‐small cell lung cancer (NSCLC). ## Methods We retrospectively analyzed the tumors