Clinical significance of P-glycoprotein expression in metastatic breast carcinoma
β Scribed by En-xiao Li; Zhong-qin He; Yuan Wu; Jing He; Yi Li
- Publisher
- Chinese Anti-Cancer Association
- Year
- 2005
- Tongue
- English
- Weight
- 330 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1000-9604
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## Abstract Twentyβfour fresh tumors of gastric carcinoma were assessed by flow cytometric detection of Pβglycoprotein (Pβgp) using monoclonal antibody C219. Eight patients were Pβgp positive. Differentiated gastric carcinomas contained significantly higher concentrations of Pβgp positive. Incidenc
In 58 human gastric cancers, the expression of P-glycoprotein (P-gp) was evaluated immunohistochemically and chemosensitivity was determined using the in vitro succinate dehydrogenase inhibition (SDI) test. Tumors which contained over 75% stained cells were scored as positive, and 14 of 58 cases (24