Macrophage metalloelastase, a member of the human matrix metalloproteinase family, is believed to play an important role in angiostatin generation, which, in experimental studies, has an antiangiogenic function and is a key molecule in tumor dormancy. However, no clinical studies have been reported
Clinical significance of miR-221 and its inverse correlation with p27Kip1in hepatocellular carcinoma
โ Scribed by Xinhui Fu; Qian Wang; Jingsong Chen; Xiaohui Huang; Xilin Chen; Liangqi Cao; Haoxiang Tan; Wen Li; Longjuan Zhang; Jiong Bi; Qiao Su; Lianzhou Chen
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 485 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0301-4851
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Background and Objectives: p27Kip1 is an inhibitor of cyclindependent kinases and is speculated to be a potential prognostic indicator in numerous human cancers. We investigated expression of p27Kip1 along with cyclin D1 in gastric cancer to estimate the clinical utility of p27Kip1. Methods: Immunoh
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