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Clinical pharmacokinetics of high-dose DTIC

✍ Scribed by José M. Buesa; Eloísa Urréchaga


Publisher
Springer
Year
1991
Tongue
English
Weight
497 KB
Volume
28
Category
Article
ISSN
0344-5704

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The pharmacokinetic profile of high-dose mitomycin C was determined in blood plasma and urine of twelve patients with advanced malignancies in a program including autologous bone marrow transplantation. A total dose of 60 mg/m2 was given, either as a single 60-min infusion or divided into infusions