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Clinical implications of DNA repair genetic alterations in cancer

โœ Scribed by L. Gossage; M. Mohammed; S. Madhusudan


Book ID
107636654
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
146 KB
Volume
2
Category
Article
ISSN
1865-5041

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โœ Herzog, Christopher R.; Lubet, Ronald A.; You, Ming ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 123 KB ๐Ÿ‘ 2 views

Specific genetic alterations affecting known tumor suppressor genes and proto-oncogenes occur during mouse lung tumorigenesis. These include mutational activation of the K-ras gene, commonly seen at a frequency of about 80% in both spontaneously occurring and chemically induced adenomas and adenocar