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Clinical Implication of Hot Spot BRAF Mutation, V599E, in Papillary Thyroid Cancers

✍ Scribed by Namba, Hiroyuki; Nakashima, Masahiro; Hayashi, Tomayoshi; Hayashida, Naomi; Maeda, Shigeto; Rogounovitch, Tatiana I.; Ohtsuru, Akira; Saenko, Vladimir A.; Kanematsu, Takashi; Yamashita, Shunichi

Book ID: 118116544
Publisher: Endocrine Society
Year: 2003
Tongue: English
Weight: 182 KB
Volume: 88
Category: Article
ISSN: 0021-972X
DOI: 10.1210/jc.2003-030305

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## Abstract ## BACKGROUND. Numerous studies have investigated the clinical significance of __BRAF__ mutation in papillary thyroid carcinoma (PTC). However, there have been conflicting data on the usefulness of __BRAF__ mutation as a prognostic marker of PTC. To address this controversy, the freque