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BRAF Mutation in Papillary Thyroid Cancer: Pathogenic Role, Molecular Bases, and Clinical Implications

✍ Scribed by Xing, Mingzhao

Book ID
118116543
Publisher
Endocrine Society
Year
2007
Tongue
English
Weight
503 KB
Volume
28
Category
Article
ISSN
0163-769X

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## Abstract The role of aberrant tumor suppressor gene methylation in the aggressiveness of papillary thyroid cancer (PTC) has not been documented. By showing promoter methylation‐induced gene silencing in PTC‐derived cell lines, we first demonstrated the functional consequence of methylation of se