✦ LIBER ✦

Clinical experience with leucovorin and 5-fluorouracil

✍ Scribed by Leslie R. Laufman; Wayne D. Brenckman Jr; Kathy A. Stydnicki; E. D. Morgan; Mary Collier; Victoria B. Knick; David S. Duch; Robert Mullin; Robert Ferone

Publisher: John Wiley and Sons
Year: 1989
Tongue: English
Weight: 493 KB
Volume: 63
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19890315)63:6+<1031::aid-cncr2820631308>3.0.co;2-1

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

5-fluorouracil with leucovorin in breast

5-fluorouracil with leucovorin in breast cancer

✍ Charles L. Loprinzi 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 247 KB 👁 1 views

Extensive preclinical data have demonstrated that leucovorin can modulate 5-fluorouracil (5-FU) cytotoxicity. Additionally, randomized clinical trials have shown that leucovorin increases the therapeutic index of 5-FU in patients with advanced colorectal cancer, setting a new therapeutic standard fo

A comprehensive review of 5-fluorouracil

A comprehensive review of 5-fluorouracil and leucovorin in patients with metastatic colorectal carcinoma

✍ David Machover 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 2 views

## Background: Colorectal carcinoma is the third leading cause of cancer-related death. the primary treatment for patients with metastatic colorectal carcinoma is systemic chemotherapy with 5-fluorouracil (5-fu) and leucovorin (lv), a biomodulator of 5-fu that has been shown to enhance its activity

5-Fluorouracil/leucovorin/interferon alp

5-Fluorouracil/leucovorin/interferon alpha-2a in patients with advanced colorectal cancer

✍ Peter B. Vermeulen; Luc Y. Dirix; Gino Pelgrims; Allan T. van Oosterom; Nanno H. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 314 KB 👁 2 views

Further clinical studies with intrahepat

Further clinical studies with intrahepatic arterial infusion with 5-fluorouracil

✍ Fred J. Ansfield; Guillermo Ramirez; Hugh L. Davis Jr.; George W. Wirtanen; Robe 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 369 KB

Toxicity and antitumor activity of 5-flu

Toxicity and antitumor activity of 5-fluorouracil in combination with leucovorin. Role of dose schedule and route of administration of leucovorin

✍ Youcef M. Rustum 📂 Article 📅 1989 🏛 John Wiley and Sons 🌐 English ⚖ 440 KB

Hypocalcemia associated with 5-fluoroura

Hypocalcemia associated with 5-fluorouracil and low dose leucovorin in patients with advanced colorectal or gastric carcinomas

✍ Yuichiro Kido; Takeshi Okamura; Morimasa Tomikawa; Manabu Yamamoto; Morio Shirai 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 367 KB 👁 2 views

## BACKGROUND. The biochemical modulation of 5-fluorouracil (5-FU) by leucovorin (Lv) has demonstrated significantly increased response rates in comparison with the use of 5-FU alone in patients with advanced colorectal carcinoma. However, the higher response rate of LV/5-FU may occur at the expen