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Clinical entity of frontotemporal dementia with motor neuron disease

✍ Scribed by Yoshio Mitsuyama; Teruhiko Inoue


Book ID
108958189
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
574 KB
Volume
29
Category
Article
ISSN
0919-6544

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Mutation within TARDBP leads to Frontote
✍ B. Borroni; C. Bonvicini; A. Alberici; E. Buratti; C. Agosti; S. Archetti; A. Pa πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 308 KB

It has been recently demonstrated that the 43-kDa transactive response (TAR)-DNA-binding protein (TARDBP) is the neuropathological hallmark of Frontotemporal Dementia (FTD) with ubiquitin-positive and tau-negative inclusions. Large series of FTD patients without motor neuron disease have been previo