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Clinical and prognostic features of patients with philadelphia chromosome-positive chronic myelogenous leukemia and extramedullary disease

✍ Scribed by Terenig Terjanian; Hagop Kantarjian; Michael Keating; Moshe Talpaz; Kenneth McCredie; Emil J. Freireich


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
348 KB
Volume
59
Category
Article
ISSN
0008-543X

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## Background: Patients with chronic myelogenous leukemia (cml) occasionally experience persistent thrombocythemia despite having adequate white blood cell (wbc) counts. trimethylenethiophosphoramide (thiotepa) is an alkylating agent that significantly inhibits platelet production. ## Methods: Th