๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Clinical and biochemical parameters of parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and its methyl-phenyl and methoxy-phenyl derivatives in C57B1/6 mice

โœ Scribed by N. I. Lermontova; L. S. Solyakov; S. O. Bachurin; T. P. Serkova; L. N. Petrova; O. A. Dranyi; S. E. Tkachenko; V. V. Kalashnikov

Publisher
Springer US
Year
1990
Tongue
English
Weight
376 KB
Volume
110
Category
Article
ISSN
0007-4888

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Levodopa-induced hyperactivity in mice t
Levodopa-induced hyperactivity in mice treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
โœ Anthony P. Nicholas ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 120 KB

The present study examines the motor responses of 10-to 12-month-old, male C57 mice that were either given intraperitoneal (IP) injections of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP; 30 mg/kg per day) or vehicle for 10 consecutive days, followed by IP injections of levodopa (200 mg/kg) pl

Methamphetamine- and 1-methyl-4-phenyl-
Methamphetamine- and 1-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice
โœ Yossef Itzhak; Julio L. Martin; Syed F. Ali ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 151 KB ๐Ÿ‘ 1 views

Previous studies have suggested a role for the retrograde messenger, nitric oxide (NO), in methamphetamine (METH)-and 1-methyl-4-phenyl-1,2,3,6tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Since evidence supported the involvement of the neuronal nitric oxide synthase (nNOS) isoform i

Conversion of 1-methyl-4-phenyl-1,2,3,6-
Conversion of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) and its 5-methyl analog into pyridinium salts
โœ Wieslaw Gessner; Arnold Brossi; Rong-Sen Shen; Richard R. Fritz; Creed W. Abell ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ German โš– 383 KB

## Abstract Monoamine oxidase B metabolizes 1โ€methylโ€4โ€phenylโ€1,2,3,6โ€tetrahydropyridine (MPTP; **1**) first to 1โ€methylโ€4โ€phenylโ€2,3โ€dihydropyridinium salt (MPDP^+^; **5**), and then to 1โ€methylโ€4โ€phenylphridinium salt (MPP^+^; **7**). Chemical synthesis of MPDP^+^ and its 5โ€methyl analog **6** wa