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Ability of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some other pyridine derivatives to cause parkinsonism

โœ Scribed by N. N. Lermontova; L. S. Solyakov; S. O. Bachurin; S. E. Tkachenko; T. P. Serkova; L. N. Petrova; V. V. Kalashnikov


Publisher
Springer US
Year
1989
Tongue
English
Weight
281 KB
Volume
107
Category
Article
ISSN
0007-4888

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Lesion of the subthalamic nucleus for th
โœ T. Z. Aziz; D. Peggs; M. A. Sambrook; Dr. A. R. Crossman ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 549 KB

Central to the neural mechanism of MPTP-induced parkinsonism is overactivity of the subthalamic nucleus. Lesion of the subthalamic nucleus has therefore been performed in two primates with this condition and found to produce a remarkable amelioration of the disorder.