Factors associated with sustained virological response (SVR) in patients treated for hepatitis C virus (HCV) recurrence after liver transplantation (LT) are unclear. Ninety-nine HCV-positive/hepatitis B surface antigen-negative patients received antiviral treatment (AVT) with interferon/peginterfero
Clevudine for chronic hepatitis B: antiviral response, predictors of response, and development of myopathy
β Scribed by J.-H. Jang; J.-W. Kim; S.-H. Jeong; H.-J. Myung; H. S. Kim; Y. S. Park; S. H. Lee; J.-H. Hwang; N. Kim; D. H. Lee
- Book ID
- 108886429
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 129 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1352-0504
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Clevudine (Revovir), a pyrimidine nucleoside analogue, is a recently introduced antiviral drug. Clinical trials have demonstrated potent, sustained antiviral activity against hepatitis B virus without specific adverse events. The lack of cytotoxicity and absence of an effect on mitochondrial functio
To identify predictors -of short-term and sustained ALT normalization after interferon treatment in adult patients with chronic hepatitis C, we performed a metanalysis of individual patients' data, with construction and cross-validation of a prediction rule, in 361 patients from two randomized trial