Novel insights into proteolytic cleavage
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Stephanie Bertram; Ilona Glowacka; Imke Steffen; Annika KΓΌhl; Stefan PΓΆhlmann
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Article
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2010
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John Wiley and Sons
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English
β 293 KB
## Abstract The influenza virus hemagglutinin (HA) mediates the first essential step in the viral life cycle, virus entry into target cells. Influenza virus HA is synthesised as a precursor protein in infected cells and requires cleavage by host cell proteases to transit into an active form. Cleava