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Role of Hemagglutinin Cleavage for the Pathogenicity of Influenza Virus

✍ Scribed by David A. Steinhauer

Book ID
112272579
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
489 KB
Volume
258
Category
Article
ISSN
0042-6822

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## Abstract The influenza virus hemagglutinin (HA) mediates the first essential step in the viral life cycle, virus entry into target cells. Influenza virus HA is synthesised as a precursor protein in infected cells and requires cleavage by host cell proteases to transit into an active form. Cleava