## Abstract __Runt__โrelated (__Runx__) transcriptional regulators play essential roles in various cell fate determination processes, and dysfunction of these regulators causes many human diseases. Considerable insight into the functions of Runx proteins was provided mainly by studies of hematopoie
โฆ LIBER โฆ
Class switch recombination in selective IgA-deficient subjects
โ Scribed by L. Hummelshoj; L. P. Ryder; L. K. Nielsen; C. H. Nielsen; L. K. Poulsen
- Book ID
- 108699370
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 352 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0009-9104
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## Abstract Immunoglobulin class switch recombination (CSR) is initiated by activationโinduced cytidine deaminase (AID), an enzyme that deaminates cytidine residues in singleโstranded DNA. U:G mismatches created by AID are processed to produce lesions that recruit and activate DNA damage response p
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