𝔖 Bobbio Scriptorium
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Claims on tissue plasminogen activator

✍ Scribed by Crespi, R. Stephen

Book ID
109757729
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
258 KB
Volume
337
Category
Article
ISSN
0028-0836

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## Abstract Tissue plasminogen activator (tPA) is the only FDA‐approved treatment of thrombotic stroke and is a major parenchymal serine protease in the brain. However, it has been implicated in a plethora of brain pathologies, raising concern about its use as a safe therapeutic. tPA is thought to