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Circulating endothelial cells predict for response to bevacizumab-based chemotherapy in metastatic colorectal cancer

✍ Scribed by Satoshi Matsusaka; Mitsukuni Suenaga; Yuji Mishima; Koichi Takagi; Yasuhito Terui; Nobuyuki Mizunuma; Kiyohiko Hatake


Publisher
Springer
Year
2010
Tongue
English
Weight
311 KB
Volume
68
Category
Article
ISSN
0344-5704

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Single nucleotide polymorphism in the 5β€²
✍ Eugenio Marcuello; Albert AltΓ©s; Elisabeth del Rio; Angeles CΓ©sar; Anna Menoyo; πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 84 KB πŸ‘ 1 views

## Abstract Thymidylate synthase (TS) is the primary target of 5‐fluorouracil (5‐FU). A VNTR polymorphism in the TS promoter region is associated with the efficacy of 5‐FU‐based chemotherapy in colorectal cancer. A common G>C SNP at the 12th nucleotide of the second repeat in the TS\*3 alleles has