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Circadian rhythm of 5-fluorouracil population pharmacokinetics in patients with metastatic colorectal cancer

✍ Scribed by Françoise Bressolle; Jean M. Joulia; Frédéric Pinguet; Marc Ychou; Cécile Astre; Jacqueline Duffour; Roberto Gomeni


Publisher
Springer
Year
1999
Tongue
English
Weight
194 KB
Volume
44
Category
Article
ISSN
0344-5704

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Thirty-eight patients with metastatic colorecal carcinoma were treated with 5-fluorouracil (5-FU), and 38 patients were treated with the combination of 5-FU, cyclophosphamide, and methotrexate. In terms of percent response, response duration, and survival there was no apparent difference between the