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Chronic non-spherocytic haemolytic disorders associated with glucose-6-phosphate dehydrogenase variants

✍ Scribed by Gemino Fiorelli; Franco Martinez di Montemuros; Maria Domenica Cappellini


Book ID
119754936
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
292 KB
Volume
13
Category
Article
ISSN
1521-6926

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More than 80 variants of glucose-6-phosphate dehydrogenase (G6PD) are associated with chronic nonspherocytic haemolytic anaemia (CNSHA); however, the molecular basis of this association is not fully understood. We have used the polymerase chain reaction and nucleotide sequence analysis to characteri